www-vendruscolo.ch cam.ac.uk

The Vendruscolo Laboratory

A rational design strategy for the selective activity enhancement of a molecular chaperone toward a target substrate. Biochemistry 2015. Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins Proc. Natl. Acad. Sci. USA 2015. Structure of a low-population intermediate state in the release of an enzyme product. eLife 2015. A molecular chaperone breaks the catalytic cycle that generates toxic Abeta oligomers. Nat. Struct. Mol. Biol. 2015.

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Vendruscolo Lab - Software Home

A method of calculating secondary structures populations of proteins from their chemical shifts. A method the prediction of protein secondary structure populations from the amino acid sequence, which predicts simultaneously structure and intrinsic disorder.

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SITE TITLE

The Vendruscolo Laboratory

DESCRIPTION

A rational design strategy for the selective activity enhancement of a molecular chaperone toward a target substrate. Biochemistry 2015. Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins Proc. Natl. Acad. Sci. USA 2015. Structure of a low-population intermediate state in the release of an enzyme product. eLife 2015. A molecular chaperone breaks the catalytic cycle that generates toxic Abeta oligomers. Nat. Struct. Mol. Biol. 2015.

PARSED CONTENT

The web page had the following on the homepage, "A rational design strategy for the selective activity enhancement of a molecular chaperone toward a target substrate." I viewed that the web site said " Rational design of antibodies targeting specific epitopes within intrinsically disordered proteins Proc." They also said " Structure of a low-population intermediate state in the release of an enzyme product. A molecular chaperone breaks the catalytic cycle that generates toxic Abeta oligomers."

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